Article
Comparative assessment of large language models for microbial phenotype assignment.
Genome biology - 23 Jul 2026
Münch Philipp C, Safaei Nasim, Mreches René, Binder Martin, Han Yichen, Robertson Gary, Franzosa Eric A, Huttenhower Curtis, McHardy Alice Carolyn
Abstract excerpt
BACKGROUND: Large language models (LLMs) are increasingly used to extract knowledge from text, yet their coverage and reliability in biology remain unclear. Microbial phenotypes are especially important to assess, as comprehensive data remain sparse except for well-studied organisms and they underpin our understanding of microbial characteristics, functional roles, and applications. RESULTS: Here, we...
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