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Article

Evolutionary analysis of Mycobacterium bovis genotypes across Africa suggests co-evolution with livestock and humans.

PLoS neglected tropical diseases - 1 Mar 2020

Inlamea Osvaldo Frederico, Soares Pedro, Ikuta Cassia Yumi, Heinemann Marcos Bryan, Achá Sara Juma, Machado Adelina, Ferreira Neto José Soares, Correia-Neves Margarida, Rito Teresa

Abstract excerpt

Mycobacterium bovis is the pathogenic agent responsible for bovine tuberculosis (bTB), a zoonotic disease affecting mostly cattle, but also transmittable to humans and wildlife. Genetic studies on M. bovis allow to detect possible routes of bTB transmission and the identification of genetic reservoirs that may provide an essential framework for public health action. We used a database with 1235 M. bovis genotypes...

Topics

Africa
Animals
Cattle
Cluster Analysis
Disease Transmission, Infectious
Genetic Variation
Genotype
Goats
Humans
Livestock
Molecular Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mycobacterium bovis

Phylogeny

Sheep

Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 32119671
DOI: 10.1371/journal.pntd.0008081
PMCID: PMC7077849

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