Popformer: Learning general signatures of positive selection with a self-supervised transformer.

Abstract excerpt

Understanding natural selection can help shed light on the genetics underpinning adaptive evolution. The widespread availability of large-scale human genetic variation data has led to the development of data-driven methods for detecting signatures of selection, many of which are based on deep learning. However, these methods often fail to generalize well to the diversity of selection signatures across a broad...

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• Algorithms
• Computational Biology
• Genetics, Population
• Genome, Human
• Haplotypes