Article
Plant-based diet, metabolic signature, genetic susceptibility, and risk of musculoskeletal disorders: a large-scale population-based prospective cohort study.
Frontiers in public health - 1 Jan 2026
Zheng Sirui, Song Xin, Yang Bin, Jin Minghao, Ma Xiaofeng, Zhang Di, Lei Bowen, Qu Yang, Xiang Rong, Zhao Xunying, Han Tao, Zhou Jinyu, Yu Ting, Xia Maoyao, Zhong Yangdan, Liu Jiawei, Li Jiayuan, Fan Mengyu, Jiang Xia
Abstract excerpt
Aims: To explore the association between plant-based diets, diet-related metabolic signatures, and the risk of total and specific musculoskeletal disorders (MSDs), while accounting for genetic susceptibility. Methods: We analyzed data from 107,983 participants in the UK Biobank. Plant-based diet indices [PDI, unhealthy PDI (uPDI), and healthy PDI (hPDI)] were calculated via 24-h dietary recalls. Elastic net...
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