Article
Thyroid function and risk of sepsis: a population-based prospective cohort study with traditional and genetic epidemiological analyses.
Frontiers in endocrinology - 1 Jan 2026
Thorkildsen Marianne S, Gustad Lise T, Åsvold Bjørn O, Mohus Randi M, Ellervik Christina, Teumer Alexander, Marouli Eirini, Medici Marco, Damås Jan K, Flatby Helene M, Rogne Tormod
Abstract excerpt
Introduction: A recent two-sample Mendelian randomization study suggested a possible causal association between hypothyroidism and selected sepsis types. We address this knowledge gap by examining the association between thyroid-stimulating hormone (TSH) levels and risk of sepsis and severe infectious diseases, using triangulation between traditional observational and Mendelian randomization (MR) analyses....
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