BATPC: A biology-anchored tumor progression classification for interpreting multidimensional progression phenotypes across solid tumors.

Abstract excerpt

BACKGROUND: Conventional size-based criteria such as RECIST collapse biologically diverse progression patterns into a single "progressive disease" label, obscuring clinically meaningful heterogeneity. As multimodal monitoring and immunotherapy become central to oncology, the lack of a standardized vocabulary for describing how tumors progress limits clinical decision-making, complicates trial interpretation, and...

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