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Article

Whole-Exome Analysis Identifies Candidate Genes Associated With Diabetic Retinopathy.

Investigative ophthalmology & visual science - 1 Jul 2026

Li Ning, Liu Long, Sun Wen, Liu Di, Li Haibin, Li Changwei, Wang Xiao, Ji Jianguang, Wen Yalu, Zheng Deqiang

Abstract excerpt

Purpose: Despite adequate glycemic control, a proportion of patients develop diabetic retinopathy (DR), suggesting the contribution of other mechanisms. To explore genetic associations with DR, we conducted a whole-exome sequencing (WES) study of DR using a dual-control design in individuals of European ancestry. Methods: Leveraging UK Biobank WES data, we implemented a dual-control design to identify candidate...

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Source

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Identifiers

PMID: 42417591
DOI: 10.1167/iovs.67.8.25
PMCID: PMC13355387

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FRZB
HK1

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