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Article

Dysregulated proteins in plasma distinguishing Loeys-Dietz syndrome from other heritable thoracic aortic disease - an explorative study.

Scandinavian cardiovascular journal : SCJ - 1 Dec 2026

Seim Bjørn Edvard, Khan Yusuf, Flesvig Holt Margrethe, Ratajska Aleksandra, Michelsen Annika, Myklebust Ringseth Monica, Lundblad Runar, Halvorsen Bente, Krohg-Sørensen Kirsten, Osnes Liv T N, Aukrust Pål, Paus Benedicte, Kvitting John-Peder Escobar, Ueland Thor

Abstract excerpt

Objectives. Thoracic aortic aneurysms (TAAs) are often found in younger individuals and approximately 20% may be associated with heritable thoracic aortic disease (HTAD). There are some data on genomic biomarkers reflecting inflammation and extracellular matrix remodelling in HTAD. However, data that accurately reflect the corresponding protein changes are scarce. Our aim was to quantify proteins by using...

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Share to Aortic Aneurysm, Thoracic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42411742
DOI: 10.1080/14017431.2026.2699504

Genes

CD5
GNLY
GP1BA
TNFRSF9
ACTA2
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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