Article

Proteomic profiling of the large vessel vasculitis spectrum identifies shared signatures of innate immune activation and stromal remodelling

2024-09-07

Abstract excerpt

Takayasu arteritis (TAK) and giant cell arteritis (GCA) are the primary forms of large vessel vasculitis (LVV) and can result in serious cardiovascular morbidity. Improved understanding of the molecular basis of these diseases is required to develop novel biomarkers and targeted treatments. Moreover, it is unclear whether shared or distinct pathogenic processes underpin the LVV spectrum. To address this, we perfor...

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Literature Corpus work: 83f81897-2130-593b-927c-d6a797a7bd08
DOI: 10.1101/2024.09.06.24313218

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