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Article

A case report of atypical hemolytic uremic syndrome with a CFH mutation complicated by recurrent posterior reversible encephalopathy syndrome.

Medicine - 3 Jul 2026

Maruyama Ryotaro, Takeuchi Daisuke, Momose Masashi, Amemiya Tetsuro, Terakawa Ion, Teshima Kenichi, Chimura Jun, Noju Kyutaro, Sugimoto Ryu, Shiroto Kosuke, Suganuma Kazuki, Yamamoto Tomokiyo

Abstract excerpt

RATIONALE: Atypical hemolytic uremic syndrome (aHUS) is a rare thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ dysfunction, particularly affecting the kidneys and the central nervous system. It is caused by genetic variants or autoantibodies involved in dysregulation of the complement system. Pathogenic variants of the complement factor H (CFH) gene...

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Share to Antibodies, Monoclonal, Humanized
Share to Atypical Hemolytic Uremic Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42410819
DOI: 10.1097/MD.0000000000049593
PMCID: PMC13337012

Genes

CFH
C5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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