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Article

Plasma resistant atypical hemolytic uremic syndrome associated with a CFH mutation treated with eculizumab: a case report.

Journal of medical case reports - 29 Apr 2015

Sevinc Mustafa, Basturk Taner, Sahutoglu Tuncay, Sakaci Tamer, Koc Yener, Ahbap Elbis, Akgol Cuneyt, Kara Ekrem, Brocklebank Vicky, Goodship Tim H J, Kavanagh David, Unsal Abdulkadir

Abstract excerpt

INTRODUCTION: Thrombotic microangiopathies are a group of diseases presenting as microangiopathic hemolytic anemia, thrombocytopenia and end-organ dysfunction. As the role of the complement system was elucidated in atypical hemolytic uremic syndrome pathogenesis, eculizumab was successfully introduced into clinical practice. We present a large pedigree with multiple individuals carrying a functionally significant...

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Share to Antibodies, Monoclonal, Humanized
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25925370
DOI: 10.1186/s13256-015-0575-y
PMCID: PMC4423495

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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