Association of GPX4 rs713041 and rs4807542 polymorphisms and serum GPX4 levels in Chinese patients with systemic lupus erythematosus.

doi:10.1177/09612033261465940

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Association of GPX4 rs713041 and rs4807542 polymorphisms and serum GPX4 levels in Chinese patients with systemic lupus erythematosus.

Lupus - 1 Oct 2026

Li Xu, Su Lin, Li Xiang, Qin Caifang, Qin Zhuo, Sun Yanan, Wei Xing, Yang Shuo, Liu Yongchao, Liu Ning, Zhang Zhihong, Wu Jiping

Abstract excerpt

Objectives: To investigate the association of serum glutathione peroxidase 4 (GPX4) levels and GPX4 polymorphisms with systemic lupus erythematosus (SLE) and lupus nephritis (LN) in a Chinese population.Methods: This hospital-based case-control study included 28 patients with LN, 28 patients with SLE without renal involvement, and 28 healthy controls for measurement of serum GPX4 levels using enzyme-linked...

Read the complete abstract on PubMed

Topics

Adult
Female
Humans
Male
Middle Aged
Case-Control Studies
China

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Enzyme-Linked Immunosorbent Assay

Genetic Predisposition to Disease

Genotype

Glutathione Peroxidase

Logistic Models

Lupus Erythematosus, Systemic

Lupus Nephritis

Phospholipid Hydroperoxide Glutathione Peroxidase

Polymorphism, Single Nucleotide

East Asian People

Source

Open in PubMed

Identifiers

PMID: 42394139
DOI: 10.1177/09612033261465940

Genes

GPX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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