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The Use of Body Mass Index Polygenic Risk Score (BMI-PRS) in a Paediatric Population With Obesity.

Pediatric obesity - 1 Jul 2026

Gomahr Julian, Lauth Wanda, Süßenbacher Lea, Bergauer Max, Forer Lotte, Eberhardt Julian, Schaffler-Schaden Dagmar, Reiter Raphael, Mörwald Katharina, Langthaler Patrick, Iglseder Bernhard, Paulweber Bernhard, Flamm Maria, Aigner Elmar, Trinka Eugen, Bito Andrea, Kiesslich Tobias, Kedenko Ludmilla, Wernly Bernhard, Weghuber Daniel

Abstract excerpt

INTRODUCTION: Polygenic risk scores (PRS) stratify obesity risk in population cohorts, but their value within specialised paediatric obesity clinics-where genetic liability may already be saturated-remains unclear. METHODS: We analysed 246 European adolescents with overweight and obesity (mean ± SD age 13.3 ± 2.2 years; 51% female; BMI 31.6 ± 4.1 kg/m2) attending a tertiary clinic in Salzburg, Austria. BMI-PRS...

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Austria
Body Mass Index
Diabetes Mellitus, Type 2
Genetic Risk Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin Resistance

Multifactorial Inheritance

Pediatric Obesity

Risk Assessment

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PMID: 42386670
DOI: 10.1111/ijpo.70132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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