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Evaluation of ctDNA in Predicting Response to Neoadjuvant Therapy and Analysis of Residual Disease in Local Advanced Gastric Cancer: Protocol of A Single-Arm Multicenter Prospective Observational Study

2023-03-30

Abstract excerpt

<h4>Background: </h4> In gastric cancer, there is a controversial finding regarding the high recurrence rate after neoadjuvant therapy. The use of ctDNA detection for minimal residual disease (MRD) with plasma genotyping has shown higher sensitivity and specificity compared to imaging and serum markers for predicting recurrence. Therefore, we aim to investigate the perioperative dynamic changes in ctDNA in surgica...

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Literature Corpus work
a221c9f4-f082-598c-ba37-b3fbb213bd37
DOI
10.21203/rs.3.rs-2698692/v1
Open publication

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Evaluation of ctDNA in Predicting Response to Neoadjuvant Therapy and Analysis of Residual Disease in Local Advanced Gastric Cancer: Protocol of A Single-Arm Multicenter Prospective Observational StudyDOI 10.21203/rs.3.rs-2698692/v1
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