Article
Prevalence of molecular markers related to artemisinin partial resistance and ACT partner drug resistance in the Plasmodium falciparum population in Kongo Central, DRC.
Malaria journal - 29 Jun 2026
Stauning Marius Ahm, Raposo Madalena, Mvuama Nono, Matela Baudouin, Tshefu Antoinette, Iversen Sissel Manscher, Sundisa Guylain, Maliwani Aline, Roper Cally, Koka Nono, Guinovart Caterina, Kurtzhals Jørgen, Okitawutshu Jean, Alifrangis Michael, Ntuku Henry, Hansson Helle
Abstract excerpt
BACKGROUND: Artemisinin-based combination therapies (ACTs) are the cornerstone of Plasmodium falciparum malaria treatment. Recent reports have documented P. falciparum with mutations associated with artemisinin partial resistance in eastern DRC, raising concerns about reduced drug susceptibility. This study examines the prevalence of mutations linked to reduced ACT efficacy in P. falciparum isolates collected...
Read the complete abstract on PubMedTopics
- Artemisinins
- Plasmodium falciparum
- Antimalarials
- Drug Resistance