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Article

Evidence of artemisinin partial resistance in northwestern Tanzania: clinical and molecular markers of resistance.

The Lancet. Infectious diseases - 1 Nov 2024

Ishengoma Deus S, Mandara Celine I, Bakari Catherine, Fola Abebe A, Madebe Rashid A, Seth Misago D, Francis Filbert, Buguzi Creyton C, Moshi Ramadhan, Garimo Issa, Lazaro Samwel, Lusasi Abdallah, Aaron Sijenunu, Chacky Frank, Mohamed Ally, Njau Ritha J A, Kitau Jovin, Rasmussen Charlotte, Bailey Jeffrey A, Juliano Jonathan J, Warsame Marian

Abstract excerpt

BACKGROUND: In 2021, nationwide malaria molecular surveillance revealed a high prevalence of a validated artemisinin resistance marker, the kelch13 (k13) Arg561His mutation, in the Kagera region of northwestern Tanzania. We aimed to investigate the efficacy of artemether-lumefantrine and artesunate-amodiaquine and to confirm the presence of artemisinin partial resistance (ART-R) in the Karagwe district of this...

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Identifiers

PMID: 39159633
DOI: 10.1016/S1473-3099(24)00362-1
PMCID: PMC11511676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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