Article
Mutational landscape in Waldenström macroglobulinemia evaluated using a next-generation sequencing lymphoma panel in routine clinical practice.
Leukemia & lymphoma - 1 Jun 2024
Østergaard Simon, Schejbel Lone, Breinholt Marie Fredslund, Pedersen Mette Ølgod, Hammer Troels, Munksgaard Lars, Nørgaard Peter, Høgdall Estrid, Gjerdrum Lise Mette Rahbek, Nielsen Torsten Holm
Abstract excerpt
Next-generation sequencing (NGS) affords comprehensive insights into the genomic landscape of lymphomas. We examined the mutational pattern in patients with Waldenström macroglobulinemia (WM) or lymphoplasmacytic lymphoma (LPL) as well as the diagnostic and clinical utility of a tailored NGS lymphoma panel. A consecutive series of 45 patients was reviewed and NGS analysis was performed as part of a routine...
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