Isolated Extreme Thrombocytosis as the Presenting Feature of Chronic Myeloid Leukemia-An Unusual Phenotype Treated With Plateletpheresis.

Abstract excerpt

Chronic myeloid leukemia (CML) can rarely present with extreme thrombocytosis as the initial manifestation, a phenotype that can mimic essential thrombocythemia, leading to delayed diagnosis. We describe the case of a 54-year-old woman who was evaluated by outpatient hematology for isolated thrombocytosis with normal iron studies and leukocyte counts. Molecular testing confirmed BCR::ABL1 fusion, consistent with...

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• Dasatinib
• ABL1 gene
• BCR gene
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive
• Phenotype