Association of ACE I/D and ACE (rs4343) polymorphism with MACE development in hypertensive patients.

doi:10.5830/CVJA-2026-006

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Association of ACE I/D and ACE (rs4343) polymorphism with MACE development in hypertensive patients.

Cardiovascular journal of Africa - 17 Apr 2026

Baig Alija, Shah Syed M M, Jan Asif, Faisal Malik, Begum Aiman, Ullah Aftab, Shah Haseenullah

Abstract excerpt

OBJECTIVE: Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide. The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) and ACE rs4343 polymorphism have been considered important and extensively studied for their association with cardiovascular conditions. This study investigates the association of this variant with the development of major adverse cardiovascular events...

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PMID: 42347749
DOI: 10.5830/CVJA-2026-006

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