Article
Association between Angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and hypertension in a Ghanaian population.
PloS one - 1 Jan 2024
Bonney Precious, Obirikorang Christian, Quaye Lawrence, Dapare Peter Paul, Adams Yussif, Bourawono Grace, Akaluti Mercy, Duodu Jemimah
Abstract excerpt
BACKGROUND: Genetic modifications in the renin-angiotensin aldosterone system (RAAS) have been suggested to play a key role in the pathophysiology of hypertension. The insertion/deletion polymorphism of angiotensin-converting enzyme (ACE) gene phenomenon and its relationship with essential hypertension has not been explored within the Ghanaian population. This study aims to determine the relationship between the...
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