Article
Phage Intolerance Impacts Antibiotic Susceptibility and Virulence in Staphylococcus aureus.
Current microbiology - 24 Jun 2026
Bowring Janine, Mikkelsen Freja C, Haider Roshni, Lehmann Esther, Frisch Thibault, Kjos Morten, van Sorge Nina M, Ingmer Hanne
Abstract excerpt
Phage therapy is a promising alternative to the growing problem of antibiotic-resistance. However, bacterial phage-resistance may develop, compromising therapy. Phage-resistance has primarily been associated with changes in phage receptors that in the human pathogen, Staphylococcus aureus, are the cell-wall linked wall teichoic acids (WTA) which can be modified by glycosylation. With the aim of identifying...
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