Article
Finerenone in Treating a 12-Year-Old Boy Suffering Gitelman Syndrome Without Causing Gynecomastia.
Nephrology (Carlton, Vic.) - 1 Jul 2026
Yin Yuhe, Lin Haowen, Gao Qingqing, Peng Siqi, Dong Xiaoying, Zhao Zewen, Li Sijia, Huang Renwei, Tao Yiming, Lin Ting, Dai Hao, Wen Feng, Li Zhuo, Xu Lixia, Feng Zhonglin, Liu Shuangxin, Ma Jianchao
Abstract excerpt
Gitelman syndrome (GS) is an autosomal recessive disorder caused by mutations in the SLC12A3 gene, characterized by hypomagnesemia, hypokalemia, alkalosis, and hypocalciuria. Finerenone, a non-steroidal mineralocorticoid receptor antagonist (MRA), has shown cardiorenal protective effects and improved prognoses in type 2 diabetes (T2DM) and chronic kidney disease (CKD). However, its use in non-diabetic nephrology...
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