Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of SIRT1 rs12778366 (T > C) polymorphism with reduced esophageal cancer risk: a case-control study from North India".

Molecular biology reports - 23 Jun 2026

Bali Jagmohan Singh, Sambyal Vasudha, Mehrotra Sanjana, Guleria Kamlesh, Uppal Manjit Singh, Manjari Mridu, Sudan Meena

Abstract excerpt

PURPOSE: The protein histone deacetylase silent mating-type information regulator 2 homolog 1 (SIRT1) expression has been linked to cancer prognosis. However, reports evaluating the impact of SIRT1 polymorphisms on esophageal cancer (EC) risk or prognosis are limited. The present study aimed to assess the association between SIRT1 rs12778366 polymorphism and esophageal cancer. MATERIALS AND METHODS: The SIRT1...

Topics

Join the communities discussing this publication.

Alleles
Case-Control Studies
Esophageal Neoplasms
Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Association Studies

Source

Identifiers

PMID: 42334702
DOI: 10.1007/s11033-026-12164-4

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of SIRT1 rs12778366 (T > C) polymorphism with reduced esophageal cancer risk: a case-control study from North India".PMID 42334702Read ↗

Association between SIRT1 Gene Polymorphisms and Breast Cancer in Egyptians.Semantic proximity Read ↗

Serum SIRT1 Levels and Gene Polymorphisms in Breast Cancer: A Biomarker and Genetic Association Study.Semantic proximity Read ↗

Association of SIRT1 single gene nucleotide polymorphisms and serum SIRT1 levels with laryngeal squamous cell carcinoma patient survival rate.Semantic proximity Read ↗

p16 gene silencing along with p53 single-nucleotide polymorphism and risk of esophageal cancer in Northeast India.Semantic proximity Read ↗

p16 hypermethylation: a biomarker for increased esophageal cancer susceptibility in high incidence region of North East India.Semantic proximity Read ↗

Association of ATG10 rs1864183, ATG16L1 rs2241880 and miR-126 with esophageal cancer.Semantic proximity Read ↗

A study on the correlation between SIRT6 gene polymorphisms and glioma risk in Chinese Han population.Semantic proximity Read ↗

Modification of risk, but not survival of esophageal cancer patients by esophageal cancer-related gene 1 Arg290Gln polymorphism: a case-control study and meta-analysis.Semantic proximity Read ↗

A variant in SIRT2 gene 3'-UTR is associated with susceptibility to colorectal cancer.Semantic proximity Read ↗

Genetic insights into bladder cancer: the impact of SIRT1 gene polymorphism.Semantic proximity Read ↗

PARP1 rs1136410 C/C genotype associated with an increased risk of esophageal cancer in smokers.Semantic proximity Read ↗

OGG1 Ser326Cys polymorphism and susceptibility to esophageal cancer in low and high at-risk populations of northern India.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.