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Article

Treatment with Hippo/YAP pathway modulators partially improves testicular and sperm phenotypes following cisplatin stimulation.

Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica - 29 Jun 2026

Pakpahan Cennikon, Faizah Zakiyatul, Amanda Bella, Hamidah Berliana, Juniastuti Juniastuti, Lusida Maria Inge

Abstract excerpt

BACKGROUND: Treatment with chemotherapeutic agents often causes side effects in male reproductive organs, which may lead to infertility. Identification of molecular targets to alleviate this effect is important to reduce the long-term effects of chemotherapeutic drugs on the reproductive capacity. In this study, we evaluated the effects of pharmacological targeting of the Hippo pathway on the male reproductive...

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Adaptor Proteins, Signal Transducing
Cisplatin
Hippo Signaling Pathway
Infertility, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

YAP-Signaling Proteins

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PMID: 42333455
DOI: 10.4081/aiua.2026.14858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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