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Article

Melatonin ameliorates paclitaxel‐induced mice spermatogenesis and fertility defects

9 Jan 2022

Abstract excerpt

Chemotherapeutic drug of paclitaxel (PTX) has been shown to cause reproductive toxicity thus affecting male fertility, but its underlying molecular basis is unclear. Melatonin (MLT) can mitigate the reproductive damage caused by certain chemotherapy drugs. In this study, we aimed to identify impact of PTX on the main biological processes and protective effect of MLT on reproductive damage caused by PTX. Mice...

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Share to Circadian rhythm and melatonin
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PMID: 35001532
DOI: 10.1111/jcmm.17177

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