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Article

DPYD polymorphisms in Native populations from the Brazilian Amazon: the absence of the variants in currently recommended clinical genotyping panels.

Pharmacogenetics and genomics - 1 Sept 2026

Suarez-Kurtz Guilherme, Basta Paulo C, Perini Jamila Alessandra

Abstract excerpt

OBJECTIVES: We examined the distribution of clinically-relevant DPYD polymorphisms in Yanomami and Munduruku individuals, from Indigenous reservation areas in the Brazilian Amazon. The estimated proportion of Native ancestry exceeded 90% in all participants. METHODS: Eight DPYD single nucleotide variants (SNVs), including rs3918290, rs55886062, rs67376798, and rs75017182, widely recognized for their established...

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 42329750
DOI: 10.1097/FPC.0000000000000611

Genes

DPYD
MAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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