Article
Molecular characteristics and clinicopathology of CTNNB1-mutated endometrial cancer: Implications for fertility-sparing management in young women.
BMC cancer - 17 Jun 2026
Li Wen-Qi, Wu Hai-Xia, Li Han-Bo, Shuai Guang-Nan, Zhang Qing, Shen Yan
Abstract excerpt
BACKGROUND: The incidence rate of endometrial cancer (EC) is increasing among young women who require fertility preservation. The identification of molecular biomarkers can improve clinical outcomes in these patients. This study evaluated the role of CTNNB1 mutations in EC and whether the CTNNB1 gene can serve as a molecular marker in fertility-sparing management. METHODS: Retrospective cohorts of patients with...
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