Phenotype-Specific Dose-Response Patterns of Systemic Inflammation With Hepatic Decompensation in Cirrhosis: A Cross-Sectional Study.

doi:10.14309/ctg.0000000000001063

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Phenotype-Specific Dose-Response Patterns of Systemic Inflammation With Hepatic Decompensation in Cirrhosis: A Cross-Sectional Study.

Clinical and translational gastroenterology - 1 Aug 2026

Zhang Shufang, Mo Xiaowei, Lai Caiting, Lv Yuanfeng, Jiang Xinjun, Lin Yue, Liu Jiakun, Li Wenting, Liu Zan

Abstract excerpt

INTRODUCTION: Systemic inflammation is associated with hepatic decompensation in cirrhosis, but whether this association follows the same dose-response pattern across different decompensation phenotypes is unknown. We examined an inflammation burden index (IBI) against severity proxies (Child-Turcotte-Pugh [CTP], Model for End-Stage Liver Disease [MELD]), and clinical events (ascites, spontaneous bacterial...

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PMID: 42308461
DOI: 10.14309/ctg.0000000000001063
PMCID: PMC13502763

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