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Article

Natural Plant Extracts Rescue Memory Deficits in Drosophila Neurodegeneration Models.

Journal of microbiology and biotechnology - 9 Jun 2026

Sang Jiun, Kang Yueyang, Lee Youngseok

Abstract excerpt

Neurodegenerative diseases are characterized by progressive impairments in cognition, stress resilience, and behavior, yet effective therapeutic interventions remain limited. Here, we performed a functional screening of Nicaraguan plant extracts using Drosophila melanogaster models of neurodegeneration-specifically Appl and DJ-1β mutants-to identify candidate extracts with neuroprotective potential. Flies were...

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Identifiers

PMID: 42305043
DOI: 10.4014/jmb.2603.03035
PMCID: PMC13275258

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