Article
Shifting genomes, rising threats: Adaptive evolution and antimicrobial resistance of E. coli ST10 across African ecologies.
Genomics - 1 Jul 2026
Malesa Refiloe, Pierneef Rian, Magwedere Kudakwashe, Mafuna Thendo, Matle Itumeleng
Abstract excerpt
Escherichia coli sequence type 10 (ST10) is an emerging zoonotic lineage with global distribution and a high antimicrobial resistance (AMR) burden, yet its population dynamics across Africa remain poorly understood. Here, we analysed 159 E. coli ST10 genomes including four newly sequenced isolates and 155 publicly available genomes from 19 African countries spanning human, animal, food, and environmental sources....
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