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Article

CD44 gene rs9666607 polymorphism is associated with papillary thyroid carcinoma and interacts with CREB3L1.

Tissue & cell - 1 Nov 2026

Ma Lili, Qu Xia, Li Xinxi, Tian Ye, Wang Bowei, Qiang Borong, Jiang Sheng, Bao Jianling, Du Guoli

Abstract excerpt

BACKGROUND: The incidence of papillary thyroid carcinoma (PTC) has been rising. CD44 is involved in cell adhesion and migration, but the role of its genetic variation in PTC remains unclear. METHODS: This study aimed to investigate the association of CD44 gene polymorphisms with PTC and to examine the interaction between CD44 and CREB3L1. This study enrolled 354 patients with PTC, and the genotype distribution of...

Read the complete abstract on PubMed

Topics

Hyaluronan Receptors
Humans
Thyroid Cancer, Papillary
Cyclic AMP Response Element-Binding Protein
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Animals

Male

Mice

Gene Expression Regulation, Neoplastic

Thyroid Neoplasms

Genetic Predisposition to Disease

Middle Aged

Cell Line, Tumor

Adult

Lymphatic Metastasis

Nerve Tissue Proteins

Source

Identifiers

PMID: 42296777
DOI: 10.1016/j.tice.2026.103686

Genes

CD44

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

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