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Article

Performance of Seven-Gene Panel Testing for Risk Stratification of Thyroid Nodules with Indeterminate Cytology Results.

International journal of molecular sciences - 30 May 2026

Jochum Ann-Kristin, Renström Frida, Bischofberger-Baumann Barbara, Demmer Izadora, Schönegg René, Brändle Michael, Bilz Stefan, Jochum Wolfram

Abstract excerpt

Risk stratification of thyroid nodules is mainly based on ultrasound examination and fine-needle aspiration (FNA) cytology findings. Molecular testing has increasingly been added to the workup to improve risk of malignancy (ROM) estimation. Here, we evaluated the diagnostic performance of alterations in seven genes, including point mutations in BRAF, HRAS, KRAS, and NRAS as well as RET/PTC1, RET/PTC3, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 42278516
DOI: 10.3390/ijms27114990
PMCID: PMC13256701

Genes

BRAF
RET
NRAS
PAX8
HRAS
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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