Article
Long-term isolation and archaic introgression shape functional genetic variation in Near Oceania.
Science (New York, N.Y.) - 11 Jun 2026
Reilly Patrick F, Rong Stephen, Tejada-Martinez Daniela, Miller Samantha L, Tjahjadi Audrey, Liu Chang, Akers Jared, Pomer Alysa, Prentice Margaret E, Merriwether D Andrew, Friedlaender Françoise R, Koki George, Friedlaender Jonathan S, Reilly Steven K, Tucci Serena
Abstract excerpt
Near Oceanic populations harbor substantial cultural, phenotypic, and genetic diversity yet are drastically underrepresented in human genomics. We generated 177 high-coverage Near Oceanian whole genomes and analyzed them alongside 1284 worldwide genomes, revealing major distinctions among and within islands, including long-term isolation and strong population bottlenecks. We reconstructed 1.897 billion base pairs...
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