Article
Intrinsic Capacity, Genetic Susceptibility and Incident Cardiovascular Disease Among Individuals With Diabetes: A Prospective Cohort Study.
Diabetes, obesity & metabolism - 1 Sept 2026
Chen Huan, Gao Jian, Zhong Wen-Fang, Li Chuan, Wang Xiao-Lin, Liu Dan, Li Zhi-Hao, Mao Chen
Abstract excerpt
BACKGROUND: The relationship between intrinsic capacity (IC), genetic susceptibility, and CVD outcomes in individuals with diabetes remains unclear. METHODS: Data were obtained from 18 333 participants with diabetes (58.63 ± 7.54 years). The IC deficit score was categorised into five levels: 0, 1, 2, 3, and 4+. Outcomes included: hypertension, IHD, stroke, PAD, HF, and AF. Genetic risk scores (PRS) were...
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