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Article

Discontinuing Colchicine in Pediatric Familial Mediterranean Fever: Real-Life Experience from a Long-Term Follow-Up Cohort.

Paediatric drugs - 1 Jul 2026

Arık Selen Duygu, Kayaalp Gülşah Kavrul, Kılınç Ayşenur Doğru, Menentoğlu Bengisu, Taşkın Büşra Başer, Dudaklı Aslı, Tanatar Ayşe, Akgün Özlem, Ayaz Nuray Aktay

Abstract excerpt

BACKGROUND: Colchicine is the cornerstone of treatment in familial Mediterranean fever and is generally recommended as lifelong therapy. However, a subset of pediatric patients may experience a milder disease course, raising questions about the feasibility and safety of colchicine discontinuation. Evidence guiding this decision remains limited, and no consensus exists on patient selection criteria or monitoring...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42270889
DOI: 10.1007/s40272-026-00755-4
PMCID: PMC13379450

Genes

MEFV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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