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Article

Clinical, genetic, and therapeutic differences in pediatric versus adult colchicine-resistant FMF patients.

Pediatrics international : official journal of the Japan Pediatric Society - 1 Jan 2026

Akyüz Dağlı Pınar, Konak Hatice Ecem, Soytürk Gülşah, Işiklar Ekici Mehveş, Kor Ahmet, Polat Bünyamin, Akif Eksin Mehmet, Babaoğlu Hakan, Çelikel Acar Banu, Erten Şükran

Abstract excerpt

BACKGROUND: Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterized by recurrent febrile episodes and serositis. Colchicine-resistant FMF represents a challenging subset of patients with more severe clinical manifestations, limited treatment options, and increased risk of long-term complications. OBJECTIVES: This study aimed to compare clinical manifestations, genetic mutations,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41782418
DOI: 10.1111/ped.70365

Genes

MEFV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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