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Article

Ultrarapid MC1R protein and associated plumage color evolution in the domestic chicken.

Proceedings of the National Academy of Sciences of the United States of America - 16 Jun 2026

Ma Cheng, Liebing Aenne-Dorothea, Kleinau Gunnar, Kamprad Antje, Calabrese Louisa, Szczepek Michal, Li Zheng, Larsson Mårten, Scheerer Patrick, Stäubert Claudia, Andersson Leif

Abstract excerpt

The domestic chicken exhibits extraordinarily high plumage diversity in sharp contrast to the uniform plumage phenotype in its wild ancestor, the red junglefowl. The melanocortin-1 receptor (MC1R) locus is the most variable pigmentation locus in domestic chicken. Here we have analyzed whole-genome sequence data from 10,026 birds, including red junglefowls and 393 populations of domestic chicken. We document...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Melanocortin, Type 1

Source

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Identifiers

PMID: 42268884
DOI: 10.1073/pnas.2605288123
PMCID: PMC13273276

Genes

MC1R

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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