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Article

Genotype Predicts Heart Failure Independent of LVEF, Peak VO2, and NT-proBNP Levels in Hypertrophic Cardiomyopathy.

JACC. Heart failure - 1 Aug 2026

Bakalakos Athanasios, Protonotarios Alexandros, Pavlou Menelaos, Cannie Douglas E, Lorca Rebeca, Coats Caroline J, Monda Emanuele, Savvatis Konstantinos, Lopes Luis R, O'Mahony Constantinos, Kaski Juan Pablo, Lorenzini Massimiliano, Syrris Petros, Elliott Perry Mark

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by left ventricular hypertrophy and progression to heart failure (HF). Approximately 40% of cases are caused by variants in genes encoding sarcomere proteins. OBJECTIVES: This study sought to determine the relationship between genotype and other clinical predictors of HF outcomes in HCM patients. METHODS: This observational,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42268168
DOI: 10.1016/j.jchf.2026.103149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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