Research progress of the correlation between genotype and phenotype in hypertrophic cardiomyopathy.

Abstract excerpt

Hypertrophic cardiomyopathy (HCM) is an autosomal dominant genetic disease characterized by left ventricular hypertrophy with prevalence of 1/500-1/200. Up to now, 1500 mutations in more than 30 genes have been found to be related to the disease. Pathogenic gene mutations together with polymorphisms of modifying genes and environmental factors play various roles in the disease processes, resulting in phenotypic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiomyopathy, Hypertrophic
• Share to Genotype
• Share to Mutation