Article
Value of Genetic Testing for the Prediction of Long-Term Outcome in Patients With Hypertrophic Cardiomyopathy.
The American journal of cardiology - 15 Sept 2016
van Velzen Hannah G, Vriesendorp Pieter A, Oldenburg Rogier A, van Slegtenhorst Marjon A, van der Velden Jolanda, Schinkel Arend F L, Michels Michelle
Abstract excerpt
Pathogenic gene mutations are found in about 50% of patients with hypertrophic cardiomyopathy (HC). Previous studies have shown an association between sarcomere mutations and medium-term outcome. The association with long-term outcome has not been described. The aim of this cohort study was to assess the long-term outcomes of patients with genotype positive (G+) and genotype negative (G-) HC. The study population...
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