Article
Genotype-positive status in patients with hypertrophic cardiomyopathy is associated with higher rates of heart failure events.
Circulation. Cardiovascular genetics - 1 Aug 2014
Li Qin, Gruner Christiane, Chan Raymond H, Care Melanie, Siminovitch Katherine, Williams Lynne, Woo Anna, Rakowski Harry
Abstract excerpt
BACKGROUND: The aim of the study was to clarify the relationship between genotype status and major cardiovascular outcomes in a large cohort of patients with hypertrophic cardiomyopathy. METHODS AND RESULTS: Genetic testing was performed in 558 consecutive proband patients with hypertrophic cardiomyopathy. Baseline and follow-up (mean follow-up 6.3 years) clinical and echocardiographic data were obtained....
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