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Article

Pre-pandemic contraction, phase-specific rate variation, and site-specific antigenic adaptation shape influenza A(H3N2) evolutionary dynamics in Hubei, China.

Journal of virology - 21 Jul 2026

Peng Mingwei, Liu Linlin, Li Xiang, Yu Xiao, Yin Qiangling, Zhang Xiaolu, Han Shi, Fang Bin

Abstract excerpt

Influenza A(H3N2) is a contributor to seasonal epidemics, yet its evolution during and after the COVID-19 pandemic is not fully understood. We analyzed surveillance data and hemagglutinin (HA) and neuraminidase (NA) sequences from Hubei, China, 2017-2024. The epidemic followed regular seasonality before 2020, nearly disappeared during 2020-2022, and resurged with strong peaks after mid-2022. Multiple HA lineages...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42267827
DOI: 10.1128/jvi.00556-26
PMCID: PMC13386829

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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