Article
Consistency of c-Met protein overexpression over time in patients with non-squamous non-small cell lung cancer.
Histopathology - 1 Sept 2026
Cortot Alexis B, Dubois Romain, Grégoire Valérie, Gibier Jean-Baptiste, Labreuche Julien, Deprez Virginie, Dubrulle Déborah, Chretien Thomas, Wasielewski Eric, Behal Hélène, Feng Dai, Lind Amber, Ansell Peter, Thiébaut-Millot Raphaële, Hader Carlos
Abstract excerpt
AIMS: The c-Met signalling pathway is dysregulated in non-small cell lung cancer (NSCLC), with c-Met protein overexpression emerging as a potentially actionable biomarker given the development of c-Met-targeted antibody-drug conjugates. This retrospective study assessed the consistency of c-Met protein overexpression over time in patients with non-squamous NSCLC and two or more longitudinal biopsy samples (one...
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