Article
Genetic and epidemiological evidence linking respiratory and musculoskeletal diseases: shared risk factors and intervention windows.
Respiratory research - 9 Jun 2026
Murrin Olivia, Voller Bethany, Woodward Ruby M, Carrasco-Ribelles Lucía A, Türkmen Deniz, Gu Qingze, Boddy Kate, Farmer Leon, Mancini Mary, Khalid Sara, Aveyard Nicholas, Fox Chris, Bowden Jack, Dudbridge Frank, Lamb Sarah E, Masoli Jane A H, Violán Concepción, Pilling Luke C, Frayling Timothy M, Delgado João
Abstract excerpt
BACKGROUND: We previously identified genetic correlation between pairs of musculoskeletal (MSK) and respiratory conditions. Strategies to prevent or delay their onset remain underexplored in the context of multimorbidity. This study investigated whether MSK-respiratory disease pairs show evidence of potential causal relationships, identified modifiable risk factors, and quantified intervention windows to prevent...
Read the complete abstract on PubMedTopics
- Humans
- Risk Factors
- Musculoskeletal Diseases
- Genetic Predisposition to Disease