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Article

RET p.Cys634-driven progression of hereditary vs. sporadic medullary thyroid cancer.

Endocrine - 8 Jun 2026

Machens Andreas, Lorenz Kerstin, Dralle Henning

Abstract excerpt

PURPOSE: Conceptually, pitting hereditary mutations, pervading all cells of the body since conception, against the same sporadic mutations, acquired by tumor cells only later in life, could give valuable insights into tumorigenesis and tumor progression. This research sought to explore RET p.Cys634-driven tumorigenesis and progression which, preceding the time of clinical detection, cannot be measured directly....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42257805
DOI: 10.1007/s12020-026-04674-9

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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