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Article

Prognostic characterization of papillary thyroid carcinoma: Insights into the role of PD-L1 and mutational landscape in disease aggressiveness and outcome.

American journal of clinical pathology - 4 Jun 2026

Rana Chanchal, Mishra Prabhakar, Makkar Isha, Singh Kulranjan, Ramakant Pooja, Mishra Anand, Chhabra Gagan

Abstract excerpt

OBJECTIVES: Papillary thyroid carcinoma (PTC) is the most common differentiated thyroid cancer, generally associated with an excellent prognosis. However, a subset of tumors behaves aggressively, highlighting the need for reliable prognostic biomarkers to improve risk stratification beyond traditional clinicopathologic parameters. This study evaluates the prognostic value of PD-L1 expression and its association...

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Share to B7-H1 Antigen
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Recurrence, Local

Share to Prognosis

Share to Proto-Oncogene Proteins B-raf

Share to Telomerase

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 42252786
DOI: 10.1093/ajcp/aqag049

Genes

BRAF
TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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