Article
Associations of accelerated phenotypic aging, genetic risk and lifestyle with incident asthma, subsequent cardiovascular disease and death: A prospective study using multi-state model.
Maturitas - 1 Jul 2026
Liu Fan, Pan Lulu, Wu Hongxian, Yu Yongfu
Abstract excerpt
OBJECTIVES: To investigate the associations of phenotypic age acceleration (PhenoAgeAccel) with the risk of dynamic progression of asthma, and whether genetic risk and lifestyle influence these associations. STUDY DESIGN: This prospective cohort study included 320,337 adults without asthma and cardiovascular disease (CVD) from the UK Biobank. PhenoAgeAccel was calculated from chronological age and nine clinical...
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