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Article

The Steroidal Profile Modulates Adaptive Immune Response and Prognosis in Adrenocortical Carcinoma: Analysis of TCR and BCR Repertoires.

Cancer medicine - 1 Jun 2026

de Souza Resende Jean Silva, Giner Igor Samesima, Muzzi João Carlos Degraf, Barbuto José Alexandre Marzagão, Lalli Enzo, Castro Mauro Antônio Alves, de Figueiredo Bonald Cavalcante

Abstract excerpt

Adrenocortical carcinoma (ACC) is a rare and aggressive malignant neoplasm with limited therapeutic options and an often poor prognosis. A deeper understanding of its interaction with the immune system is essential for the advancement of personalized treatment strategies, particularly in light of the tumor heterogeneity of hormone production. ACC tumors can be classified into high steroid phenotype (HSP) and low...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphocytes, Tumor-Infiltrating

Share to Receptors, Antigen, B-Cell

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Source

Open in PubMed Open full text

Identifiers

PMID: 42249652
DOI: 10.1002/cam4.71781
PMCID: PMC13241620

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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