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Article

Long-Term Fragility of Y Chromosomes Is Dominated by Short-Term Resolution of Sexual Antagonism.

Genetics - 1 Dec 2017

Blackmon Heath, Brandvain Yaniv

Abstract excerpt

The evolution of heteromorphic sex chromosomes has fascinated biologists, inspiring theoretical models, experimental studies, and studies of genome structure. This work has produced a clear model, in which heteromorphic sex chromosomes result from repeated fixations of inversions (or other recombination suppression mechanisms) that tether sexually antagonistic alleles to sex-determining regions, followed by the...

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Topics

Alleles
Aneuploidy
Chromosome Inversion
Chromosomes, Human, X
Chromosomes, Human, Y
Evolution, Molecular
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Klinefelter Syndrome

Male

Meiosis

Selection, Genetic

Turner Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 29021279
DOI: 10.1534/genetics.117.300382
PMCID: PMC5714469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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