Role of the RNF213 Variant in Vascular Outcomes in Patients With Intracranial Atherosclerosis.

Abstract excerpt

Background The RNF213 (ring finger protein 213 gene) variant R4810K is a susceptibility allele not only for Moyamoya disease (MMD) but also for intracranial atherosclerosis (ICAS) in East Asian populations. We hypothesized that this variant would affect the distribution of ICAS and recurrence of cerebrovascular events. Methods and Results We conducted a prospective study of patients with ICAS and MMD using...

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• Adenosine Triphosphatases
• Asia, Eastern
• Intracranial Arteriosclerosis
• Moyamoya Disease
• Plaque, Atherosclerotic